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Tenofovir disoproxil
Tenofovir disoproxil is an antiretroviral medication used to prevent and treat HIV/AIDS and to treat chronic hepatitis B.〔(【引用サイトリンク】url=http://www.drugs.com/monograph/viread.html )〕 The active substance is in fact tenofovir, while tenofovir disoproxil is a prodrug that is used because of its better absorption in the gut.
The drug is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. It is marketed by Gilead Sciences under the trade name Viread (as the fumarate, TDF).
==Medical uses==
* HIV-1 infection: Tenofovir is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients 2 years of age and older.〔 This indication is based on analyses of plasma HIV-1 RNA levels and CD4 cell counts in controlled studies of tenofovir in treatment-naive and treatment-experienced adults.
* Tenofovir is indicated for the treatment of chronic hepatitis B in adults and pediatric patients 12 years of age and older.〔〔(Guidelines for the prevention, care and treatment of persons with chronic hepatitis B infection ), WHO, Publication details:Pages: 166 Publication date: March 2015 Languages: English ISBN 978 92 4 154905 9〕
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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